Endocrine Abstracts

The incidence of Alzheimer’s disease (AD) is higher in women than men. Our study aimed to investigate the behavioral, biochemical, and histological changes in lipopolysaccharide (LPS)-induced AD, to study effect of estrogen in AD clarifying the possible involved underlying mechanisms and its modulation by progestsserone. Groups: Female albino rats were divided into control, AD, AD+ovariectomy (OVX), AD+OVX+estrogen replacement and AD+OVX+estrogen+pr...

Recent reports on the interplay between adiponectin, thyroid hormones and metformin have given conflicting results. Our study aimed to investigate adiponectin concentration in thyroid disorders and to assess the possibility of involvement of adiponectin in the regulation of thyroid hormone production, also to clarify the role of pituitary-thyroid axis in the modulation of adiponectin production and to assess the interplay between metformin treatment, thyroid function and adipo...